BDBM182901 US9676732, 35 6-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-4-isopropyl-2-methyl-pyrazolo[4,3-d]pyrimidine-5,7-dione

SMILES CC(C)n1c2cn(C)nc2c(=O)n(-c2c(F)cc(cc2F)C#Cc2ccccc2)c1=O

InChI Key InChIKey=OGGREJJJLSDMSD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182901   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM182901(US9676732, 35 6-[2,6-Difluoro-4-(2-phenylethynyl)p...)
Affinity DataEC50:  30nMAssay Description:About 24 hrs before an experiment, 5×10^4 cells/well were seeded in poly-D-lysine coated, black/clear-bottomed 96-well plates. The cells were loaded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent